Comparing Generation X to Generation Y on work-related beliefs.

A new generation of employees with new expectations is entering the workplace. They are known by many names, but most will recognize them as the Millennials or Generation Y (Gen Y). With many Gen Y members already in the workforce, managers are likely to be required to deal with the generational differences that appear to exist among employees. Given that Gen Y members are likely to work closely with Gen X members, the present study explored possible differences between Gen X and Gen Y on their work-related beliefs

FABP-2 and PPAR-γ Haplotype as Risk Factors for Dyslipidemia in a Type 2 Diabetes Mellitus Population of Santa Rosa del Conlara, San Luis, Argentina

Introduction: Type 2 Diabetes Mellitus (T2DM) is a complex disorder caused by the interaction between genetic predisposition and environmental factors. Genetics plays an important role on lipid homeostasis. Many genes are involved in the lipid metabolism, such as FABP-2 and PPAR-γ. Aim: To evaluate the association between specific SNPs and haplotypes of the FABP-2 and PPAR-γ genes with T2DM and lipid profile in an Argentinean population. Methods: The FABP-2 (rs1799883) and PPAR-γ (rs1801282) polymorphisms were genotyped and analyzed in association with lipid profile and T2DM, separately and also combined in haplotypes. Results: The frequency of the rare Thr54 allele of the FABP-2 polymorphism in control (0.33) was not different from the frequency in T2DM (0.27), whereas the frequency of the rare Ala12 allele of the PPAR-γ polymorphism in control was different from the frequency in T2DM (0.26 and 0.14, respectively; p = 0.0031). Frequencies of haplotypes for these two single-nucleotide polymorphisms differed significantly in control and T2DM. Haplotype association analysis showed the associations between ThrPro haplotype and TG levels (OR = 2.520; 95% CI = 1.139 - 5.575; p = 0.027) and between ThrPro haplotype and TC and LDL-c levels when compared to AlaPro haplotype (difference = 0.175, 95% CI = 0068 - 0.499, p < 0.0001; difference = 0.052, 95% CI = 0.017 - 0.158, p < 0.0001, respectively). Conclusions: These results from a haplotype analysis show for the first time that genetic combinations of alleles of the FABP-2 and PPAR-γ gene could play a role in the susceptibility to develop dyslipemia in T2DM.Fil: Siewert, Susana Elfrida. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas. Laboratorio de Diabetes; ArgentinaFil: Olmos Nicotra, Maria Florencia. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas. Laboratorio de Diabetes; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Gonzalez, Irma Ines. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas. Laboratorio de Diabetes; ArgentinaFil: Fernandez, Gustavo. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas. Laboratorio de Diabetes; ArgentinaFil: Ojeda, Marta Susana. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas. Laboratorio de Diabetes; Argentin

The Role of Natriuretic peptides in Renovascular Hypertension and its correlation with the Evolution of Myocardial Hypertrophy

The interactions between pressure and volume overload that occur in hypertension lead to different patterns of cardiac hypertrophy and to increase in natriuretic peptides (NPs). The profiles of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) synthesis and secretion have been investigated in models of hypertension. However, the different evolution of these profiles during the acute and chronic periods of pressure overload-induced cardiac hypertrophy is still unknown. For this reason, we studied one-kidney, one clip model using Sprague-Dawley rats at weeks 2, 4, 6 and 12 and correlated the evolution of these profiles with cardiac hypertrophy and hypertension. We observed a positive correlation between blood pressure elevation and the degree of cardiac hypertrophy, with a time-dependent increase in both parameters from week 2. Levels of BNP expression showed an early increase after 2 weeks of treatment while ANP increased significantly after 6 weeks. Yet, the increase in ANP expression was gradual, allowing its correlation with hypertrophy and hypertension. The NP expression has a differential response in the early stages of the development of hypertrophy induced by the renovascular model, with an early increase in BNP expression. Once hypertrophy develops, BNP expression is no longer specific and the increase of both NPs depends on and correlates with the degree of cardiac hypertrophy.Fil: Cerrudo, Carolina Susana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Cavallero, Carmen Susana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Rodríguez Fermepin, Martin. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Hertig, Cecilia Margarita. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; ArgentinaFil: Fernandez, Belisario Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentin

Factors influencing salt-induced weathering of building sandstone.

The role of chemical cleaning in causing salt-induced weathering of building sandstone was investigated by looking at the changes in a series of weathering indicators selected. These were mainly, porosity and pore size distribution changes, chemical composition and colour changes. Laboratory studies involved the use of artificial weathering studies. Samples of Locharbriggs and Crossland Hill sandstones were first studied after partial immersion in salt-contaminated solutions. No temperature variation or humidity cycling was promoted. Samples were then exposed to cycles of humidity and temperature that simulate wet/dry cycles based on field data from a representative Scottish environment. Additional studies involved exposure of samples to SO2 gas and water spray at acid pH. These studies aimed at understanding the effects of environmental factors (relative humidity, temperature, SO2 and pH) which can promote salt- induced weathering of building stone. Weathering studies carried out on chemical cleaned samples have not been reported previously, and therefore represented a novel use of temperature and humidity controlled chambers. The possibility of environmental/climatic influence on the action of salts in sandstone by means of different intensity on dry/wet cycles, salt crystallisation and salt migration was also studied by exposing the samples to four different locations in Scotland (Banff, rural-coastal; Dunkeld, rural-inland; Aberdeen, urban-coastal and Glasgow, urban-inland) after being chemically cleaned. The analysis of the field exposure data involved statistical analysis and especially multivariate methods of the damage salts against the environmental data. In general, the indicators selected showed the following trends independently of having a control (not cleaned) or a chemical cleaned sample: porosity decreased, and most ions presented a similar distribution pattern after field exposure

MODELLING TOURISM DEMAND: A COMPARATIVE STUDY BETWEEN ARTIFICIAL NEURAL NETWORKS AND THE BOX-JENKINS METHODOLOGY

This study seeks to investigate and highlight the usefulness of the Artificial Neural Networks (ANN) methodology as an alternative to the Box-Jenkins methodology in analysing tourism demand. To this end, each of the above-mentioned methodologies is centred on the treatment, analysis and modelling of the tourism time series: “Nights Spent in Hotel Accommodation per Month”, recorded in the period from January 1987 to December 2006, since this is one of the variables that best expresses effective demand. The study was undertaken for the North and Centre regions of Portugal. The results showed that the model produced by using the ANN methodology presented satisfactory statistical and adjustment qualities, suggesting that it is suitable for modelling and forecasting the reference series, when compared with the model produced by using the Box?Jenkins methodology.Artificial Neural Networks; ARIMA Models; Time Series Forecasting

La violencia: ¿Un problema de salud mental en el Perú? Violence: A problem of mental health in Peru

WHO defines mental health as a condition in which a person is aware of his or her abilities to face the problems of everyday life, performs productively in his or her workplace, and contributes to his or her community. During 2017, according to the Ministry of Health in Peru, 52,611 people were treated on an outpatient basis for mental health among victims of family violence and patients with different mental disorders. The number of victims of family violence was 18,387.La OMS define la salud mental como una condición en la cual la persona es consciente de sus capacidades,puede enfrentar los problemas de la vida diaria, desempeñarse de forma productiva en su centro laboral ycontribuir con su comunidad. Según el Ministerio de Salud, en el Perú durante el año 2017 se atendieron52 611 personas de manera ambulatoria por salud mental entre víctimas de violencia familiar y pacientescon diferentes trastornos mentales, siendo el número de víctimas de violencia familiar 18 387

A Combined View of Sterile-Neutrino Constraints from CMB and Neutrino Oscillation Measurements

We perform a comparative analysis of constraints on sterile neutrinos from the Planck experiment and from current and future neutrino oscillation experiments (MINOS, IceCube, SBN). For the first time, we express the Planck constraints on $N_{\rm eff}$ and $m_{\rm eff}^{\rm sterile}$ from the Cosmic Microwave Background in the parameter space used by oscillation experiments using both mass-squared differences and mixing angles. In a model with a single sterile neutrino species and using standard assumptions, we find that the Planck data and the oscillation experiments measuring muon-neutrino disappearance have similar sensitivity.Comment: 6 pages, 3 figures, Version accepted by Physics Letters B, minor changes to text, results unchange

Oral proficiency in second and third foreign languages in the Danish education system

In this paper, we analyze how oral proficiency is understood in the Danish education system in the three biggest second/third foreign languages taught in the country: French, Spanish and German. We adopt a comparative perspective and analyze how orality is addressed in these language subjects at primary school, secondary school and university levels. We compare the three languages to find similarities and differences, focusing on learning objectives, pedagogical approaches and examination forms, presented in the official curricula for each of the three educational levels. We relate the Danish stance on oral proficiency to current international research in the field and to European tendencies.peerReviewe

Cambios en transaminasas hepáticas inducidas por ketoconazol en tratamiento de dermatofitosis en Canis familiaris, distrito de Trujillo

Se evaluaron 60 Canis familiaris de diferentes edades, razas y sexos, de los cuales 30 pacientes fueron clínicamente sanos y 30 presentaron dermatofitosis, diagnosticados mediante el raspado cutáneo, con la finalidad de evaluar los cambios en transaminasas hepáticas alanin amino transferasa (ALT) y aspartato amino transferasa (AST) inducidos por ketoconazol en tratamiento de dermatofitosis en el distrito de Trujillo; a los cuales se les administró, como terapia, ketoconazol vía oral a dosis de 10 mg/kg cada 24 horas, durante un periodo de 20 días continuos. Se observó que pacientes con dermatofitosis mostraron un incremento pre tratamiento de las transaminasas respecto a los perros sanos; sin embargo, al iniciar el tratamiento hasta la culminación del mismo no se obtuvo diferencias estadísticas significativas en ambas enzimas, hecho que advierte que el ketoconazol no produce hepatotoxicidad a la dosis usada y por el periodo descrito en perros con dermatofitosis. Los efectos adversos más comunes en los pacientes fueron vómitos, diarreas y anorexia; sin embargo, no fueron inconveniente para cortar la terapia, llegando a concluir todos los tratamientos.60 dogs of different age, race, and gender were evaluated, of which 30 patients were clinically healthy and 30 present dermatophytosis, diagnosed by skin scraping; with the aim to evaluate the changes of hepatic transaminase alanin amino transferase (ALT) and aspartate amino transferase (AST) induced by ketoconazol in dermatophytosis treatment of Canis familiaris in Trujillo district. Which are given as oral ketoconazole therapy at a dose of 10 mg / kg every 24 hours over a period of 20 continuous days. It was observed that patients with dermatophytosis showed a pre-treatment increment of transaminase over healthy dogs; however, from the begining of the treatment to its completion it was not obtained statistically significant differences in both enzymes, this fact warns us that ketoconazol does not produce hepatotoxicity to the dose and for the described period of time in dogs with dermatophytosis. The most common adverse effects in patients were vomit, diarrhea and anorexia; but these were not inconvenient to stop therapy, concluding all treatments.Tesi